Solid State NMR Lab

Solid State NMR (nuclear magnetic resonance) is an effective technique capable of looking at a variety of materials.
The solid state NMR facility utilizes state of the art technology to enable researchers to better understand the molecular structure and composition of solid samples.  In addition, our lab provides expertise in interpreting solid state NMR spectra.  Fields studied are diverse and include:

Organics (Fine Chemicals, Pharmaceutics)
McCollum Laboratory University of Kansas Organometallics
Catalysts, Reactive Intermediates
Mixtures (e.g., Pharmaceutical Formulations)
Biomass, Plant Materials (Plant Stalk, Leaves)
Soils, Sediments
Energy Materials (Coal, Shale, Battery Materials)
Polymers, Proteins
Membranes, Tissues, Gels

Research Contributions
Mixtures of molecular species can be analyzed in order to identify what species are present and how much of it.  Also possible, is the determination of the degree of crosslinking in polymers, the degree of incorporation of metals into catalysts and the change in composition of plant materials from different treatments.

Characterization of materials in solid state
  • Crystalline polymorphs
  • Crystal vs. amorphous
  • Influence of particle size, crystal quality, bulk environment
  • Lot-to-lot variation
  • Can isolate components of mixtures (e.g., drug and excipient)
  • Conformation, arrangement, degree of disorder
  • Dynamics- –lattice mobility, glass transition (Tg)
More information available from solids
  • Orientation-dependent interactions
  • Dipolar couplings
  • Chemical shift anisotropy (fingerprint)
  • Complicated spectra
  • Line broadening from multiple phenomena
 

 


CONTACT

Justin Douglas
Director
phone785-864-4187
emailjustindouglas@ku.edu

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